Tuesday, February 25, 2020

Ethical and Moral Philosophies Research Paper Example | Topics and Well Written Essays - 750 words

Ethical and Moral Philosophies - Research Paper Example There are moral philosophies that come in handy when business decisions are made by business people to ensure it falls within the realms of their morals and achieve business goals (Forsyth, 1992). These include teleology, egoism, utilitarianism, relativist, virtue ethics, and justice but this study will elaborate on idealism and relativism. One of the moral philosophies applied in business decision-making include idealism where a decision-maker considers the welfare of others in choosing the decision to make. Highly idealistic individual’s belief in the presence of measures to avoid harming others and will not decide to chose a lesser evil between two evils that will negatively affect other people. Lowly idealistic people belief in the assumption that little harm may be necessary for good to be produced, hence if their decision will harm less people they would chose it among two harmful evils (Forsyth, 1992). Relativism is the other example of moral philosophy applied in business decision-making where a decision maker uses their selves or the people around them as a basis for defining ethical standards (Ferrell et al., 2013). High relativist individuals make a decision depending on the individuals and that the nature of the situation and circumstances are weighed more than ethical principles. Low relativist individuals base their decisions on ensuring they are consistent with moral principles, norms, and practices. Moral philosophies influence behavior and decision-making because when a person takes on a given moral philosophy either consciously or unconsciously, the moral philosophy becomes his/her guiding principle. The person carries out the moral philosophy relentlessly through each obstacle in his way. He/she will strategize and make ways through which the given moral philosophy will be beneficial to them as an

Sunday, February 9, 2020

Drug Development and Toxicology (High-performance liquid Essay

Drug Development and Toxicology (High-performance liquid chromatography) - Essay Example is also vital in actiation of various carcinogens and detoxification of toxic epoxides (Bauer, Faiola, Abernethy, Marchan, Pluta, Wong, Gonzalez, Butterworth, Borghoff, Everitt and Recio, 2003). The deficiency of epoxide hydrolase does not show any abnormal phenotype. This suggests that it is not important for physiological homeostasis and reproduction. However, deficiency in epoxide hydrolase results in the organism been unable to bioactivate DMBA to the carcinogenic metabolite. This results in the organism been highly resistant to DMBA induced carcinogenesis. Its deficiency causes a decrease in reaction to toxicity that is as a result of benzene as there is a reduction in the quantity of metabolites that are toxic (Bauer, Faiola, Abernethy, Marchan, Pluta, Wong, Gonzalez, Butterworth, Borghoff, Everitt and Recio, 2003). As shown in the test results, the concentration of 4, 5 – dihydrodiol reduces day after day. This means that the catalysis of epoxide hydrolase leads to its reduction. This means that the toxicity of 4, 5 – dihydrodiol is relatively reduced. For 7, 8 – dihydrodiol, the catalysis of epoxide hydrolase leads to its complete reduction. Hence, it is rendered non-toxic. The concentration of 7, 8 – diol – 9, 10 – epoxide continually rises after each day. This means that the inhibition of the catalysis of 7, 8 – diol – 9, 10 – epoxide by epoxide hydrolase leads to a rise in the concentration of this metabolite which results in an increase in its toxicity. Mr. X is likely to develop a cancer as a result of this accident. From the graph, it can be inferred on that the concentration of 7, 8 – diol – 9, 10 – epoxide gradually increases. This metabolite is not inactivated but is resistant to epoxide hydrolase and increased in quantity. This increase in concentration increases the likelihood of Mr. X developing cancer. The reason for this is, due to its resistanse to catalysis by epoxide hydrolase, this metabolite causes mutation in